Multidrug Resistance
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Multidrug Resistance Definition
Simultaneous resistance to a spectrum of unrelated drugs following exposure to a single agent. It may result from overexpression of the integral plasma membrane protein, P-glycoprotein. This adaptation of tumor cells to anticancer drugs, mediated by inactivation of the drug or removing it from the target tumor cells, tends to make the drugs less effective.
Multidrug Resistance Synonyms
Multidrug Resistance, Multiple Drug Resistance, multidrug resistance
Terms in Multidrug Resistance category
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