Cancer Terms

Multiple Membrane Spanning Receptor-TRC8

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Ligase -> Multiple Membrane Spanning Receptor-TRC8

Multiple Membrane Spanning Receptor-TRC8 Definition

Encoded by human TRC8 Gene, Multiple Membrane Spanning Receptor TRC8 is a multi-membrane spanning ER protein containing a RING-H2 zinc finger with ubiquitin ligase activity. TRC8 may interact with tumor suppressor protein VHL as well as with COPS5/JAB1, responsible for degradation of tumor suppressor CDKN1B/p27KIP. (NCI)

Multiple Membrane Spanning Receptor-TRC8 Synonyms

Multiple Membrane Spanning Receptor TRC8, Patched Related Protein TRC8, RNF139, Ring Finger 139, TRC8

Terms in Multiple Membrane Spanning Receptor-TRC8 category



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