Cancer Terms

Mutation

Cancer Terms -> Biological Process -> Subcellular Process -> Biochemical Process -> Molecular Sequence Alteration -> DNA Sequence Alteration -> Mutation

Mutation Definition

Permanent, transmissible changes in the genetic material of an organism. Mutations can range from a single base change to the loss of a significant portion of a chromosome. These occur when DNA is not repaired prior to replication. Mutations in germ cells can be inherited. However, in somatic cells, they are not inherited. Somatic mutations can arise via exposure to chemical mutagens or ionizing radiation. These fixed changes in the genetic material can, in some cases, lead to cancer or other diseases.

Mutation Synonyms

Mutation, Genetic Alteration, Genetic Change, Mutated, mutation

Terms in Mutation category

Base Pair Miscoding
Deletion Mutation
Gene Mutation
Germline Mutation
Induced Mutation
Insertion Mutation
Point Mutation
Somatic Mutation
UV-Mutagenesis
3 Flank Mutation
5 Flank Mutation



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