NAD-Binding Domain

Cancer Terms -> Anatomic Structure System or Substance -> Microanatomy -> Macromolecular Structure -> Protein Structure -> Protein Domain -> Ligand Binding Domain -> NAD-Binding Domain

NAD-Binding Domain Definition

The Gly-rich NAD-Binding Domain (often N-terminal) is often found in metabolic enzymes involved in glycolysis, glyconeogenesis, and the citric acid cycle, such as GAPDH (glyceraldehyde-3-phosphate oxidation and phosphorylation), lactate dehydrogenases (lactate to pyruvate conversion), and malate dehydrogenases (malate to oxaloacetate interconversion). (NCI)

NAD-Binding Domain Synonyms

NAD-Binding Domain, NAD-Binding Fold

Terms in NAD-Binding Domain category

GXGXXXG Motif