NF-Kappa B p49-p100 Protein

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Transcription Regulatory Protein -> Transcription Factor -> NF-Kappa B p49-p100 Protein

NF-Kappa B p49-p100 Protein Definition

NF-Kappa B p49/p100 is the precursor of the NFKB p52 subunit. NFKB2 belongs to the Rel/Dorsal family, contains seven ANK repeats, and binds to REL (p65) proteins to form NFKB, which is trapped in the cytoplasm by IkB proteins. IkB phosphorylation by IKBKA or IKBKB activates NFKB via destructive ubiquitination of IkBs. Activated transcription factor NFKB translocates to the nucleus and binds to the consensus Kappa-B enhancer DNA motif in immune response and acute phase reaction genes. (from SWISS-PROT Q00653, OMIM 164012, and NCI)

NF-Kappa B p49-p100 Protein Synonyms

NF-Kappa B p49/p100, H2TF1, LYT10 Protein, NF-kB Subunit 2, NF-kappa-B2, NF-kappaB(p50), NFKB p49/p100 Subunit, NFKB2, NFKB2 Protein, Nuclear Factor Kappa B Subunit 2, Nuclear Factor Kappa-B Subunit 2, Nuclear Factor NF-Kappa-B P100 Subunit, Nuclear Factor of Kappa Light Chain Gene Enhancer in B-Cells 2, Transcription Factor NFKB2

NF-Kappa B p49-p100 Protein

NF-Kappa B p49-p100 Protein Definition

NF-Kappa B p49-p100 Protein Synonyms

Terms in NF-Kappa B p49-p100 Protein category