Cancer Terms

NMYC wt Allele

Cancer Terms -> Gene -> Transcription Factor Gene -> MYC Family Gene -> NMYC Gene -> NMYC wt Allele

NMYC wt Allele Definition

Human MYCN wild-type allele is located in the vicinity of 2p24.1 and is approximately 6 kb in length. This allele, which encodes N-myc proto-oncogene protein, is involved in the modulation of transcription by RNA polymerase II. The gene is expressed at elevated levels in neuroblastoma, retinoblastoma, small cell lung carcinoma and astrocytoma.

NMYC wt Allele Synonyms

MYCN wt Allele, MODED, MYCN, N-myc, NMYC, ODED, v-MYC Myelocytomatosis Viral Related Oncogene, Neuroblastoma Derived (Avian) wt Allele

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