Cancer Terms

NR3C1 wt Allele

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> Receptor Gene -> Nuclear Receptor Gene -> NR3C1 Gene -> NR3C1 wt Allele

NR3C1 wt Allele Definition

Human NR3C1 wild-type allele is located in the vicinity of 5q31.3 and is approximately 125 kb in length. This allele, which encodes glucocorticoid receptor protein, is involved in transcriptional regulation that affects a variety of processes such as blood glucose concentration, protein/fat metabolism, inflammatory responses, cellular proliferation, and differentiation. Mutations in the gene are a primary cause of glucocorticoid resistance, or cortisol resistance.

NR3C1 wt Allele Synonyms

NR3C1 wt Allele, GCR, GR, GRL, NR3C1, Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) wt Allele

Terms in NR3C1 wt Allele category



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