NUDT1 wt Allele
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NUDT1 wt Allele Definition
Human NUDT1 wild-type allele is located within 7p22 and is approximately 9 kb in length. This allele, which encodes 7,8-dihydro-8-oxoguanine triphosphatase protein, is involved in the hydrolysis of 8-oxo-dGTP in the free nucleotide pool. Overexpression of the NUDT1 gene is associated with several types of cancer such as non-small-cell lung carcinomas, renal cell carcinomas and prostate cancer.
NUDT1 wt Allele Synonyms
NUDT1 wt Allele, MTH1, Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 wt Allele
Terms in NUDT1 wt Allele category
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