NUP214 wt Allele

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> Transport Protein Gene -> Nucleoporin Gene -> NUP214 Gene -> NUP214 wt Allele

NUP214 wt Allele Definition

Human NUP214 wild-type allele is located in the vicinity of 9q34.1 and is approximately 108 kb in length. This allele, which encodes nuclear pore complex protein Nup214, plays a role in the regulation of nucleocytoplasmic transport and receptor-mediated nuclear import. The 3 prime portion of the gene can form a fusion construct with the DEK gene on chromosome 6 in a t(6,9) translocation. The translocation is associated with acute myeloid leukemia and myelodysplastic syndrome.

NUP214 wt Allele Synonyms

NUP214 wt Allele, CAIN, CAN, D9S46E, KIAA0023, N214, NUP214, Nucleoporin 214kDa wt Allele

NUP214 wt Allele

NUP214 wt Allele Definition

NUP214 wt Allele Synonyms

Terms in NUP214 wt Allele category