Nelarabine
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Nelarabine Definition
An arabinonucleoside antimetabolite with antineoplastic activity. Nelarabine is demethoxylated by adenosine deaminase to become biologically active 9-beta-D-arabinosylguanine (ara-G); ara-G incorporates into DNA, thereby inhibiting DNA synthesis and inducing an S phase-dependent apoptosis of tumor cells. (NCI04)
Nelarabine Synonyms
Nelarabine, 2-Amino, 6-Methoxypurine Arabinoside, 2-Amino-6-methoxypurine arabinoside, 2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine, 506U78, Arranon, Compound 506U78, GW506U78, NELARABINE
Terms in Nelarabine category
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