Neuropeptide-Y

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Neuropeptide -> Neuropeptide-Y

Neuropeptide-Y Definition

Encoded by single copy human NPY Gene (NPY Family), 97-aa 11-kDa (precursor) secreted Neuropeptide Y is a 36-aa peptide neuromodulator with sequence homology to peptide YY and PNP. One of the most abundant widespread peptides in the nervous system and found in some adrenal medulla chromaffin cells, NPY is one of the most highly conserved peptides known; only 3 amino acid differences exist between human and shark. Implicated in control of feeding, energy balance, and secretion of GNRH, NPY may also regulate angiogenesis. NPY regulates proliferation of multipotent postnatal neuronal precursor or basal cells by PKC-dependent rapid and transient activation of ERK1/2 MAP kinases (via NPY Y1 receptor subtype). (NCI)

Neuropeptide-Y Synonyms

Neuropeptide Y, NPY, Neuropeptide Tyrosine

Neuropeptide-Y

Neuropeptide-Y Definition

Neuropeptide-Y Synonyms

Terms in Neuropeptide-Y category