Nifedipine
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Calcium Channel Blocker -> Nifedipine
Nifedipine Definition
A dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04)
Nifedipine Synonyms
Nifedipine, Adalat, NIFEDIPINE, Procardia
Terms in Nifedipine category
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