Nitazoxanide
Cancer Terms ->
Drugs and Chemicals ->
Pharmacologic Substance ->
Anti-Infective Agent ->
Antiparasitic Agent ->
Antiprotozoal Agent -> Nitazoxanide
Nitazoxanide Definition
A synthetic benzamide with antiprotozoal activity. Nitazoxanide exerts its antiprotozoal activity by interfering with the pyruvate ferredoxin/flavodoxin oxidoreductase dependent electron transfer reaction, which is essential to anaerobic energy metabolism. PFOR enzyme reduces nitazoxanide, thereby impairing the energy metabolism. However, interference with the PFOR enzyme-dependent electron transfer reaction may not be the only pathway by which nitazoxanide exhibits antiprotozoal activity. Nitazoxanide is active against Giardia lamblia and Cryptosporidium parvum.
Nitazoxanide Synonyms
Nitazoxanide, Alinia, Benzamide, 2-(acetyloxy)-N-(5-nitro-2-thiazolyl)-, NITAZOXANIDE, Salicylamide, N-(5-nitro-2-thiazolyl)-, Acetate(Ester)
Terms in Nitazoxanide category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.