Cancer Terms

Non-Receptor Type 7 Protein Tyrosine Phosphatase

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Hydrolase -> Phosphatase -> Phosphoprotein Phosphatase -> Protein Tyrosine Phosphatase -> Non-Receptor Type 7 Protein Tyrosine Phosphatase

Non-Receptor Type 7 Protein Tyrosine Phosphatase Definition

Preferentially expressed as 2 distinct alternative isoforms in thymic and spleen hematopoietic cells by human early response PTPN7 Gene (Non-Receptor PTP Family) in lymphokine-stimulated cells, cytoplasmic Non-Receptor Type 7 Protein Tyrosine Phosphatase is likely involved in regulation of TCR signaling through dephosphorylating MAP kinase pathway molecules; the noncatalytic N-terminus interacts with and suppresses MAP kinase activities. PTPN7 appears to regulate T and B lymphocyte development and signal transduction. Protein Tyrosine Phosphatases typically regulate cellular processes including cell growth, differentiation, and mitotic cycle. (NCI)

Non-Receptor Type 7 Protein Tyrosine Phosphatase Synonyms

Protein Tyrosine Phosphatase, Non-Receptor Type 7, Hematopoietic Protein Tyrosine Phosphatase, PTPN7, Protein Tyrosine Phosphatase LC-PTP

Terms in Non-Receptor Type 7 Protein Tyrosine Phosphatase category



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