Nuclear Receptor Coactivator-5
Cancer Terms ->
Gene Product ->
Protein ->
Protein Organized by Function ->
Regulatory Protein ->
Transcription Regulatory Protein ->
Transcription Coactivator -> Nuclear Receptor Coactivator-5
Nuclear Receptor Coactivator-5 Definition
Widely expressed by human NCOA5 Gene, 579-aa 66-kDa Nuclear Receptor Coactivator 5 contains an LXXLL motif essential for association with nuclear receptors and acts as a coregulator for ESR1, ESR2, and orphan nuclear receptor NR1D2. NCOA5 interacts with ESR1 and ESR2 independently of the steroid binding AF2 domain that regulates interaction with other coreceptors. NCOA5 exerts both coactivator and corepressor functions. (NCI)
Nuclear Receptor Coactivator-5 Synonyms
Nuclear Receptor Coactivator 5, CIA, Coactivator Independent of AF2, NCOA5
Terms in Nuclear Receptor Coactivator-5 category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.