Cancer Terms

OK-432

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Biological Response Modifier -> Immunoadjuvant -> Chemo Immunostimulant Adjuvant -> OK-432

OK-432 Definition

A lyophilized formulation containing cultures of a low-virulent strain of Streptococcus pyogenes, treated and killed with pencillin G, with potential sclerosing, immunostimulating and antineoplastic activity. Besides from picibanil's direct damaging effect as a sclerosing agent, it seems to have multiple effects on the immune system as a non-specific immunostimulant. Picibanil activates the host immune system by stimulating the activity of natural killer cells, macrophages and lymphocytes, and by enhancing the production of several key immune mediators, including interleukins and tumor necrosis factor.

OK-432 Synonyms

Picibanil, OK-432

Terms in OK-432 category



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