OTF-2
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Homeobox Protein -> OTF-2
OTF-2 Definition
Encoded by human POU2F2 Gene (POU2 Family), alternative isoforms 1 (478-aa, 51-kD), 2 (466-aa), 3 (462-aa), and 4 (399-aa) of transcription factor OTF-2 contain a DNA binding homeobox domain, bind to octamer motif ATTTGCAT, and regulate Ig gene expression and transcription in several other tissues. OTF-2 also interacts with transcription activators NR3C1, AR, and PGR. Neuronal NOS gene is a target of OTF-2. (from LocusLink, Swiss-Prot, OMIM, and NCI)
OTF-2 Synonyms
POU Domain, Class 2, Transcription Factor 2, Lymphoid-Restricted Immunoglobulin Octamer Binding Protein NF-A2, Lymphoid-Specific OTF2, OCT-2, OTF-2, Octamer Transcription Factor-2, Octamer-Binding Transcription Factor 2, POU Homeodomain Transcription Factor 2, POU2F2
Terms in OTF-2 category
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