Oncogene ABL1
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Oncogene ABL1 Definition
Human v-abl Abelson murine leukemia viral oncogene homolog 1 (ABL1) gene, located at 9q34.1, encodes proto-oncogene tyrosine-protein kinase ABL1 protein. Alternative splicing of this gene produces two protein isoforms. A t(9;22) translocation, resulting in the fusion of the BCR and ABL1 genes, has been detected in many cases of chronic myelogeneous leukemia.. This BCR-ABL fusion gene is also present in acute myeloid leukemia and acute lymphoblastic leukemia.
Oncogene ABL1 Synonyms
Oncogene ABL1, ABL, Abelson Murine Leukemia Viral Oncogene Homolog, Oncogene, ABL, Oncogene, ABL1
Terms in Oncogene ABL1 category
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