Oncogene AP2

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Oncogene AP2 Definition

Human transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (TFAP2A) gene, located at 6p24, encodes transcription factor AP-2 alpha. This gene is developmentally regulated and expression is induced by retinoic acid. Alternative splicing of the AP2 gene produces four mRNA transcripts, resulting in four protein isoforms. One of these proteins is a negative regulator of transcriptional activation by AP-2.

Oncogene AP2 Synonyms

Oncogene AP2, Activator Protein 2 Gene

Terms in Oncogene AP2 category

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