Oncogene ETS
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Oncogene ETS Definition
Oncogene ETS was originally discovered as a chimeric component, along with a truncated v-myb gene, in the genome of E26, an avian leukosis virus. ETS1 encodes 42-52 kD nuclear phosphoprotein transcription factors that interact with purine-rich promoter/enhancer sequences in the TCRA gene. ETS1 also regulates p16(INK4A) gene expression. The human gene is located at 11q23.3.
Oncogene ETS Synonyms
Oncogene ETS, E26 Transformation Specific Oncogene, ETS
Terms in Oncogene ETS category
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