Oncogene LMYC

Cancer Terms -> Gene -> Cancer Gene -> Oncogene -> Oncogene Transcription Factor -> MYC-Family Oncogene -> Oncogene LMYC

Oncogene LMYC Definition

Human Oncogene LMYC is a mutated variant of LMYC Gene (MYC Family), which encodes L-MYC Protein, a bZIP transcription factor that binds to DNA as a heterodimer with MAX; DNA binding requires dimerization with another bHLH protein. The gene is amplified 10- to 20-fold in small-cell lung cancer (SCCL). Several LMYC mRNAs are produced in SCCL cells by alternative splicing and alternative polyadenylation. Oncogene LMYC disrupts normal cell function.

Oncogene LMYC Synonyms

Oncogene LMYC, MYC Related Gene From Lung Cancer

Terms in Oncogene LMYC category

---

Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.