Ondansetron Hydrochloride
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Ondansetron Hydrochloride Definition
The hydrochloride salt of the racemic form of ondansetron, a carbazole derivative and a selective, competitive serotonin 5-hydroxytrptamine type 3 (5-HT3) receptor antagonist with antiemetic activity. Although its mechanism of action has not been fully characterized, ondansetron appears to competitively block the action of serotonin at 5HT3 receptors peripherally in the gastrointestinal tract as well as centrally in the area postrema of the CNS, where the chemoreceptor trigger zone (CTZ) for vomiting is located, resulting in the suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.
Ondansetron Hydrochloride Synonyms
Ondansetron Hydrochloride, GR 38032F, GR-C507/75, ONDANSETRON HYDROCHLORIDE, SN-307, Zofran
Terms in Ondansetron Hydrochloride category
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