Cancer Terms

Oral Akt Inhibitor GSK2110183

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Enzyme Inhibitor -> Protein Kinase Inhibitor -> Serine Threonine Kinase Inhibitor -> Oral Akt Inhibitor GSK2110183

Oral Akt Inhibitor GSK2110183 Definition

An orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GSK2110183 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents.

Oral Akt Inhibitor GSK2110183 Synonyms

Oral Akt Inhibitor GSK2110183, GSK2110183

Terms in Oral Akt Inhibitor GSK2110183 category



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