Oral Akt Inhibitor GSK2110183
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Oral Akt Inhibitor GSK2110183 Definition
An orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GSK2110183 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents.
Oral Akt Inhibitor GSK2110183 Synonyms
Oral Akt Inhibitor GSK2110183, GSK2110183
Terms in Oral Akt Inhibitor GSK2110183 category
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