Cancer Terms

Organic Cation Transporter-Like 2 Protein

Cancer Terms -> Retired Concepts -> Retired Concept 2003 -> Organic Cation Transporter-Like 2 Protein

Organic Cation Transporter-Like 2 Protein Definition

Encoded by human SLC22A1L Gene (Polyspecific Transporter/Multidrug Resistance Family), 424-amino acid Organic Cation Transporter-Like 2 Protein has ten transmembrane segments. Highest expression occurs in liver, heart, and kidney. The SLC22A1L organic cation transporter protein is localized on the apical surface of renal proximal tubules and appears to confer resistance/transport activity to chloroquine and quinidine-related compounds. Renal epithelial cell apical and basolateral polyspecific organic-cation transporters mediate excretion of endogenous and exogenous compounds. (from OMIM and NCI)

Organic Cation Transporter-Like 2 Protein Synonyms

Organic Cation Transporter-Like 2 Protein, Imprinted Polyspecific Membrane Transporter 1, Solute Carrier Family 22, Organic Cation Transporter, Member 1-Like, Tumor-Suppressing STF 5

Terms in Organic Cation Transporter-Like 2 Protein category



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