Oxcarbazepine
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Oxcarbazepine Definition
A dibenzazepine carboxamide derivative with an anticonvulsant property. As a prodrug, oxcarbazepine is converted to its active metabolite, 10-monohydroxy. Although the mechanism of action has not been fully elucidated, electrophysiological studies indicate this agent blocks voltage-gated sodium channels, thereby stabilizing hyper-excited neural membranes, inhibiting repetitive neuronal firing, and decreasing the propagation of synaptic impulses.
Oxcarbazepine Synonyms
Oxcarbazepine, 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide, OXCARBAZEPINE, Trileptal
Terms in Oxcarbazepine category
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