Cancer Terms

PARP Inhibitor MK4827

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Enzyme Inhibitor -> Poly ADP-Ribose Polymerase Inhibitor -> PARP Inhibitor MK4827

PARP Inhibitor MK4827 Definition

An inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. PARP Inhibitor MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis. The PARP family of proteins detect and repair single strand DNA breaks by the base-excision repair (BER) pathway. The specific PARP family member target for PARP inhibitor MK4827 is unknown.

PARP Inhibitor MK4827 Synonyms

PARP Inhibitor MK4827

Terms in PARP Inhibitor MK4827 category



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