Cancer Terms

PAX5 wt Allele

Cancer Terms -> Gene -> Regulatory Gene -> Transcription Coregulator Gene -> Transcription Coactivator Gene -> PAX5 Gene -> PAX5 wt Allele

PAX5 wt Allele Definition

Human PAX5 wild-type allele is located in the vicinity of 9p13 and is approximately 201 kb in length. This allele, which encodes paired box gene Pax-5 protein, is involved in transcriptional activation during B-cell differentiation, neural development and spermatogenesis. In some lymphomas, the expression of the wild-type allele is elevated as a result of a translocation t(9;14)(p13;q32).

PAX5 wt Allele Synonyms

PAX5 wt Allele, BSAP, PAX5 Beta, PAX5 Beta Gene, Paired Box Gene 5 (B-Cell Lineage Specific Activator) wt Allele

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