Cancer Terms

PF-03814735

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Enzyme Inhibitor -> Protein Kinase Inhibitor -> Serine Threonine Kinase Inhibitor -> Aurora Kinase Inhibitor -> PF-03814735

PF-03814735 Definition

An aurora kinase inhibitor with potential antineoplastic activity. PF-03814735 binds to and inhibits aurora kinases, serine-threonine kinases that play essential roles in mitotic checkpoint control during mitosis. Inhibition of aurora kinases may result in an inhibition of cellular division and proliferation in tumor cells that overexpress aurora kinases.

PF-03814735 Synonyms

Aurora Kinase Inhibitor PF-03814735, PF-03814735

Terms in PF-03814735 category



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