POLB wt Allele

Cancer Terms -> Gene -> Enzyme Gene -> Transferase Gene -> Polymerase Gene -> POLB Gene -> POLB wt Allele

POLB wt Allele Definition

Human POLB wild-type allele is located in the vicinity of 8p11.2 and is approximately 33 kb in length. This allele, which encodes DNA polymerase beta protein, plays a role in DNA base excision repair which entails gap-filling DNA synthesis in a stepwise, distributive fashion. Defects in the POLB gene are associated with certain forms of cancer such as cervical and esophageal cancer.

POLB wt Allele Synonyms

POLB wt Allele, Polymerase (DNA Directed), Beta wt Allele

Terms in POLB wt Allele category

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