Cancer Terms

POU Domain

Cancer Terms -> Anatomic Structure System or Substance -> Microanatomy -> Macromolecular Structure -> Protein Structure -> Protein Domain -> Ligand Binding Domain -> DNA Binding Domain -> Helix-Turn-Helix Motif -> POU Domain

POU Domain Definition

The POU domain is a bipartite DNA binding domain recognized originally as a shared structural motif in the Pit-1, Oct-1/Oct-2, and Unc-86 transcription factors (POU). It is comprised by a C-terminal homeo domain, and an N-terminal POU-specific domain, separated by a non-conserved linker. The POU-specific domain, like the homeo domain, is folded in a helix-turn-helix motif.

POU Domain Synonyms

POU Domain

Terms in POU Domain category



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