Cancer Terms

PR-Domain Zinc Finger Protein-1

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Transcription Regulatory Protein -> Transcription Repressor Corepressor -> PR-Domain Zinc Finger Protein-1

PR-Domain Zinc Finger Protein-1 Definition

Expression by human PRDM1 Gene increased on virus induction, 789-aa 88-kDa PR-Domain Zinc Finger Protein 1 is a transcriptional repressor containing a SET domain and 4 C2H2-type zinc fingers. PRDM1 specifically binds to the PRDI (positive regulatory domain I) element of the beta-IFN gene promoter and represses beta-interferon gene expression. PRDM1 also drives maturation of B lymphocytes into Ig secreting cells. (NCI)

PR-Domain Zinc Finger Protein-1 Synonyms

PR-Domain Zinc Finger Protein 1, B-Lymphocyte-Induced Maturation Protein 1, BLIMP1, Beta-Interferon Gene Positive-Regulatory Domain I Binding Factor, PR Domain Containing 1 with ZNF Domain Protein, PRDI-BF1, PRDI-Binding Factor-1, PRDM1, Positive Regulatory Domain I-Binding Factor 1

Terms in PR-Domain Zinc Finger Protein-1 category



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