PTEN wt Allele

Cancer Terms -> Gene -> Signaling Pathway Gene -> PTEN Gene -> PTEN wt Allele

PTEN wt Allele Definition

Human PTEN wild type allele is located in the vicinity of 10q23.3 and is approximately 109 kb in length. This allele, which encodes phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN protein, plays a role in multiple signal transduction pathways. The wild-type allele influences cellular proliferation, survival, adhesion, migration and cell cycle progression through the modulation of the phosphorylation state of both phosphoinositides and focal adhesion kinase. Mutated forms of the gene are found in a large number of cancers.

PTEN wt Allele Synonyms

PTEN wt Allele, BZS, MHAM, MMAC1, PTEN1, Phosphatase and Tensin Homolog, Phosphatase and Tensin Homolog (Mutated in Multiple Advanced Cancers 1) wt Allele, TEP1

PTEN wt Allele

PTEN wt Allele Definition

PTEN wt Allele Synonyms

Terms in PTEN wt Allele category