PTN wt Allele

Cancer Terms -> Gene -> Growth Factor Gene -> PTN Gene -> PTN wt Allele

PTN wt Allele Definition

Human PTN wild-type allele is located within 12p12.1-p11.2 and is approximately 14 kb in length. This allele, which encodes pleiotrophin protein, plays a role in mitogenesis for endothelial, epithelial, and fibroblast cells and neurite outgrowth. Further, aberrations of the gene result in allelic variants that are implicated in tumor invasion, angiogenesis, and metastasis.

PTN wt Allele Synonyms

PTN wt Allele, HARP, HBGF8, HBNF, NEGF-1, NEGF1, Pleiotrophin (Heparin Binding Growth Factor 8, Neurite Growth-Promoting Factor 1) wt Allele

Terms in PTN wt Allele category

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