Paclitaxel PPE Microspheres
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Paclitaxel PPE Microspheres Definition
A paclitaxel formulation containing paclitaxel incorporated in biodegradable polyphosphoester (PPE) polymer form with potential antineoplastic activity. Upon intraperitoneal delivery, paclitaxel PPE microspheres slowly and continuously dissolve and deliver paclitaxel to the tumor site, where it binds to tubulin and inhibits the dynamics of disassembly-assembly of microtubules. As a result, this formulation induces cell cycle arrest and leads to cell death.
Paclitaxel PPE Microspheres Synonyms
Paclitaxel PPE Microspheres, Paclimer Microspheres, Paclimer Microspheres (Polilactofate/Paclitaxel), Paclitaxel Biopolymer Formulation
Terms in Paclitaxel PPE Microspheres category
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