Paired Box Protein Pax-7
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Paired Box Protein Pax-7 Definition
Paired Box Protein Pax-7, encoded by the PAX7 gene, is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of Paired Box Protein Pax-7 is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown. (from LocusLink)
Paired Box Protein Pax-7 Synonyms
Paired Box Protein Pax-7, HUP1, PAX7, Paired Box Gene 7, Paired Box Homeotic Gene 7, Paired Domain Gene 7, Paired Domain Gene HuP1
Terms in Paired Box Protein Pax-7 category
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