Palladium-Bacteriochlorophyll Derivative WST11

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Photosensitizing Agent -> Palladium-Bacteriochlorophyll Derivative WST11

Palladium-Bacteriochlorophyll Derivative WST11 Definition

A vascular-acting photosensitizer consisting of a water-soluble, palladium-substituted bacteriochlorophyll derivative with potential antineoplastic activity. Upon administration, paldeliporfin is activated locally when the tumor bed is exposed to low-power laser light; reactive oxygen species (ROS) are formed upon activation and ROS-mediated necrosis may occur at the site of interaction between the photosensitizer, light and oxygen. Vascular-targeted photodynamic therapy (VTP) with padeliporfin may allow tumor-site specific cytotoxicity while sparing adjacent normal tissues.

Palladium-Bacteriochlorophyll Derivative WST11 Synonyms

Padeliporfin, Palladium-Bacteriochlorophyll Derivative WST11, WST11

Terms in Palladium-Bacteriochlorophyll Derivative WST11 category

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