Pan HER VEGFR2 Receptor Tyrosine Kinase Inhibitor BMS-690154
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Pan HER VEGFR2 Receptor Tyrosine Kinase Inhibitor BMS-690154 Definition
A pyrrolotriazine-based compound and a pan inhibitor of receptor tyrosine kinases with potential antineoplastic activity. Pan HER/VEGFR2 receptor tyrosine kinase inhibitor BMS-690154 binds to human epidermal growth factor receptors 1 and 2 (HER1, HER2) and vascular endothelial growth factor receptor 2 (VEGFR-2), all three of which are frequently overexpressed by a variety of tumor types. Binding of this agent to these receptors may result in the inhibition of tumor cell proliferation; the inhibition of endothelial cell migration and proliferation and angiogenesis; and tumor cell death.
Pan HER VEGFR2 Receptor Tyrosine Kinase Inhibitor BMS-690154 Synonyms
Pan HER/VEGFR2 Receptor Tyrosine Kinase Inhibitor BMS-690154, BMS-690154
Terms in Pan HER VEGFR2 Receptor Tyrosine Kinase Inhibitor BMS-690154 category
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