Cancer Terms

Pantoprazole

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Agent Affecting Digestive System Or Metabolism -> Anti-ulcer Agent -> Proton Pump Inhibitor -> Pantoprazole

Pantoprazole Definition

A substituted benzimidazole and proton pump inhibitor with antacid activity. Pantoprazole is a lipophilic weak base that crosses the parietal cell membrane and enters the acidic parietal cell canaliculus where it becomes protonated, producing the active metabolite sulphenamide, which forms an irreversible covalent bond with two sites of the H+/K+-ATPase enzyme located on the gastric parietal cell, thereby inhibiting both basal and stimulated gastric acid production.

Pantoprazole Synonyms

Pantoprazole, PANTOPRAZOLE

Terms in Pantoprazole category



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