Cancer Terms

Pemirolast

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Agent Affecting Respiratory System -> Anti-asthmatic Agent -> Mast Cell Stabilizer -> Pemirolast

Pemirolast Definition

A pyrimidinone derivative with anti-allergic activity. Pemirolast blocks the antigen-mediated calcium ion influx into mast cells. This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, such as histamine and leukotrienes, which are involved in the allergic process. Pemirolast also prevents inflammatory mediator release from eosinophils.

Pemirolast Synonyms

Pemirolast, PEMIROLAST

Terms in Pemirolast category



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