Cancer Terms

Penbutolol

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Agent Affecting Nervous System -> Adrenergic Agent -> Adrenergic Antagonist -> Beta-Adrenergic Blocking Agent -> Penbutolol

Penbutolol Definition

A lipophilic, nonselective beta-adrenergic receptor antagonist with anti-anginal and antihypertensive activities. Penbutolol competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, penbutolol prevents the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels.

Penbutolol Synonyms

Penbutolol, PENBUTOLOL

Terms in Penbutolol category



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