Penclomedine
Cancer Terms ->
Drugs and Chemicals ->
Pharmacologic Substance ->
Antineoplastic Agent ->
Alkylating Agent ->
Antineoplastic Alkylating Agent ->
Picoline Compound -> Penclomedine
Penclomedine Definition
A synthetic derivative of pyrimidine with antineoplastic activity. Penclomedine alkylates and crosslinks DNA, resulting in DNA strand breaks and inhibition of DNA and RNA synthesis. This agent is more active against tumor cells that are defective in p53 function. (NCI04)
Penclomedine Synonyms
Penclomedine, 3,5-dichloro-2,4-dimethoxy-6-(trichloromethyl) pyridine, CRC 88-04, PEN, Pyridine, 3,5-dichloro-2,4-dimethoxy-6-(trichloromethyl)-, penclomedine
Terms in Penclomedine category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.