Cancer Terms

Pentetic Acid

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Protective Agent -> Chelating Agent -> Pentetic Acid

Pentetic Acid Definition

An edetate and a chelating agent used in preparing radiopharmaceuticals. Pentetic acid (DTPA) has strong affinity for iron but also shows affinities for other heavy metals, thereby is used in the treatment of iron-storage disease and poisoning from heavy and radioactive metals. DTPA may chelate metallic moieties of unbound, extracellular radioimmunotherapeutics, thereby aggregating radioimmunotherapeutics locally to higher concentrations, and improving tumor cell radiocytotoxicity, while sparing normal tissues from the radiocytotoxic effects. In addition, DTPA is used in radioimaing procedures when complexes with radioisotopes, ex., Tc 99m or In 111.

Pentetic Acid Synonyms

Pentetic Acid, (Diethylenetriamine)pentaacetic acid, DTPA, Detapac, Detarex, Diethylenetriamine Pentaacetic Acid, PENTETIC ACID

Terms in Pentetic Acid category



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