Cancer Terms

Perfosfamide

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Alkylating Agent -> Antineoplastic Alkylating Agent -> Mustard Agent -> Nitrogen Mustard Compound -> Perfosfamide

Perfosfamide Definition

The active metabolite of the nitrogen mustard cyclophosphamide with potent antineoplastic and immunosuppressive properties. Perfosfamide alkylates DNA, thereby inhibiting DNA replication and RNA and protein synthesis. (NCI04)

Perfosfamide Synonyms

Perfosfamide, 2-[bis(2-chloroethyl)amino]-4-hydroperoxytetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide, 4'-Hydroperoxycyclophosphamide, 4-HC, 4-Hydroperoxycyclophosphamide, 4-Pergamid, Hydroperoxycyclophosphamide, Pergamid, cis-2-[bis(2-chloroethyl)amino]tetrahydro-3H-1,3,2-oxazaphosphorin-4-yl hydroperoxide P-oxide, cis-4-hydroperoxycyclophosphamide

Terms in Perfosfamide category



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