Cancer Terms

Peroxisome Proliferator-Activated Receptor Binding Protein

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Peroxisome Proliferator-Activated Receptor Binding Protein Definition

TRAP220 (thyroid hormone receptor-associated protein) is a recently cloned nuclear receptor coactivator, which interacts with several nuclear receptors in a ligand-dependent manner and stimulates transcription by recruiting the TRAP mediator complex to hormone responsive promoter regions. TRAP220 has been shown to interact with thyroid hormone receptors, vitamin D receptors, peroxisome proliferator-activated receptors, retinoic acid receptors and estrogen receptors. Our work supports the assumption that TRAP220 plays an important role in growth and differentiation of central nervous system and may have a function in certain areas of adult brain. (from Eur J Neurosci. 2002;16:671-83)

Peroxisome Proliferator-Activated Receptor Binding Protein Synonyms

Peroxisome Proliferator-Activated Receptor Binding Protein, PPAR Binding Protein, PPARBP, PPARG Binding Protein, TRAP220, Thyroid Hormone Receptor-Associated Protein Complex, 220 KDa Subunit, Thyroid Receptor Interacting Protein 2

Terms in Peroxisome Proliferator-Activated Receptor Binding Protein category



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