Phosphatidylinositol-4-Phosphate-5-Kinase Type-II Alpha
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Phosphatidylinositol-4-Phosphate-5-Kinase Type-II Alpha Definition
Expressed ubiquitously (high in brain) by human PIP5K2A Gene (PtdIns(4)P-5-Kinase Family), 406-aa 46-kDa Phosphatidylinositol-4-Phosphate 5-Kinase Type II Alpha is a likely homodimer that catalyzes the phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-biphosphate, the precursor to second messengers of phosphoinositide signal transduction pathways involved in regulation of secretion, cell proliferation, differentiation, and motility. PIP5K2A does not show homology to other kinases, but the protein does exhibit kinase activity. (NCI)
Phosphatidylinositol-4-Phosphate-5-Kinase Type-II Alpha Synonyms
Phosphatidylinositol-4-Phosphate 5-Kinase Type II Alpha, 1-Phosphatidylinositol-4-Phosphate 5-Kinase, 1-Phosphatidylinositol-4-Phosphate Kinase, Diphosphoinositide Kinase, PIP5K2A, PIP5KII-Alpha, PIPK, PtdIns(4)P-5-Kinase, Type II Phosphatidylinositol-4-Phosphate 5-Kinase 53 K
Terms in Phosphatidylinositol-4-Phosphate-5-Kinase Type-II Alpha category
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