Phosphoinositide-3-Kinase Catalytic Gamma Polypeptide

Cancer Terms -> Gene Product -> Protein -> Protein Complex Subunit -> Phosphoinositide-3-Kinase Catalytic Gamma Polypeptide

Phosphoinositide-3-Kinase Catalytic Gamma Polypeptide Definition

Phosphoinositide-3-Kinase, Catalytic, Gamma Polypeptide, encoded by the PIK3CG gene, belongs to the PI3/PI4-kinase family of proteins. This protein is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. (from LocusLink)

Phosphoinositide-3-Kinase Catalytic Gamma Polypeptide Synonyms

Phosphoinositide-3-Kinase Catalytic Gamma Polypeptide, 1-Phosphatidylinositol 3-Kinase, EC 2.7.1.153, PI3-Kinase, PI3-Kinase p110 Subunit Gamma, PI3K, PI3KGamma, PIK3CG, PTDINS-3-Kinase, Phosphatidylinositol 3 Kinase Gamma, p110 Gamma, Phosphatidylinositol 3-Kinase Catalytic 110-kD Gamma, Phosphatidylinositol 3-Kinase, Catalytic, Gamma Polypeptide, Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit, Gamma Isoform, Phosphoinositide-3-Kinase Gamma Catalytic Subunit, PtdIns-3-Kinase p110, p110-Gamma

Phosphoinositide-3-Kinase Catalytic Gamma Polypeptide

Phosphoinositide-3-Kinase Catalytic Gamma Polypeptide Definition

Phosphoinositide-3-Kinase Catalytic Gamma Polypeptide Synonyms

Terms in Phosphoinositide-3-Kinase Catalytic Gamma Polypeptide category