Phospholipase-C Gamma-2
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Phospholipase -> Phospholipase-C Gamma-2
Phospholipase-C Gamma-2 Definition
Encoded by human PLCG2 Gene, 1265-aa 148-kDa Phospholipase C Gamma 2 is a crucial enzyme that generates DAG and IP3 second messengers in the transmembrane signaling of ligand-activated growth factor receptors. Containing a PI-PLC X-box catalytic domain, a PI-PLC Y-box catalytic domain, a C2 domain, a PH domain, 2 SH2 domains, and an SH3 domain, PLCG2 phospholipase activity increases upon phosphorylation on tyrosine residues following activation of growth factor and immune system receptors. (NCI)
Phospholipase-C Gamma-2 Synonyms
Phospholipase C Gamma 2, 1-Phosphatidylinositol Phosphodiesterase, 1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Gamma 2, EC 3.1.4.11, PI-Specific PLC Gamma, PLC-Gamma-2, PLC-IV, PLCG2, Phosphatidylinositol-Specific Phospholipase C-Gamma, Phosphoinositide Phospholipase C, Phospholipase C, Gamma 2 (Phosphatidylyinositol-specific), Phospholipase C-Gamma-2
Terms in Phospholipase-C Gamma-2 category
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