Piperazinedione
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Antineoplastic Alkylating Agent -> Piperazinedione
Piperazinedione Definition
A crystalline antibiotic fermentation product isolated from the bacterium Streptomyces griseoluteus with antineoplastic activity. Piperazinedione alkylates DNA at the N-7 position of guanine, inhibiting DNA replication and inducing cell cycle arrest.
Piperazinedione Synonyms
Piperazinedione, 2, 5-Piperazinedione, 3,6-bis-(5-chloro-2-piperidyl)-, dihydrochloride, 2, 5-piperazinedione, 3,6-bis-(5-chloro-2-piperidyl)-, dihydrochloride, 2,5-Piperazinedione, 3, 6-bis(5-chloro-2-piperidinyl)-, dihydrochloride, [3S-[3.alpha.(2S*,5R*),6.alpha.(2S*,5R*)]]- (9CI), 2,5-piperazinedione, 3, 6-bis(5-chloro-2-piperidinyl)-, dihydrochloride, [3S-[3.alpha.(2S*,5R*),6.alpha.(2S*,5R*)]]- (9CI), 593A, Compound 593A, Merck Compound 593A, PZD, PZD dihydrochloride, 3,6-bis(5-chloro-2-piperidinyl)-, dihydrochloride
Terms in Piperazinedione category
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