Cancer Terms

Pixantrone

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> DNA Binding Agent -> Intercalating Agent -> Pixantrone

Pixantrone Definition

A synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity.

Pixantrone Synonyms

Pixantrone, 6,9-Bis((2-aminoethyl)amino)benzo(g)isoquinoline-5,10-dione, PIXANTRONE

Terms in Pixantrone category



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