Pixantrone
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Pixantrone Definition
A synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity.
Pixantrone Synonyms
Pixantrone, 6,9-Bis((2-aminoethyl)amino)benzo(g)isoquinoline-5,10-dione, PIXANTRONE
Terms in Pixantrone category
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