Cancer Terms

Pixantrone Dimaleate

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> DNA Binding Agent -> Intercalating Agent -> Pixantrone Dimaleate

Pixantrone Dimaleate Definition

The dimaleate salt of a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity.

Pixantrone Dimaleate Synonyms

Pixantrone Dimaleate, BBR 2778, Benz(g)isoquinoline-5,10-dione, 6,9-bis((2-aminoethyl)amino)-, (2Z)-2-butenedioate (1:2), PIXANTRONE DIMALEATE, Pixantrone Maleate

Terms in Pixantrone Dimaleate category



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